SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION;AMOREPACIFIC CORPORATION
发明人:
Ah Reum KIM,Su Na KIM,Won Seok PARK,Yoo Wook KWON,Young Bae PARK,Hyo Soo KIM,Jae Seung PAEK
申请号：
US14779136
公开号：
US20160215269A1
申请日:
2014.10.16
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present disclosure relates to a method for inducing pluripotent stem cells by inducing reprogramming and/or dedifferentiation of differentiated adult cells using shikimic acid, a plant extract or plant stem cells containing shikimic acid and an extract of dedifferentiated stem cells (callus), pluripotent stem cells prepared by the method and a composition containing the pluripotent stem cells. In accordance with the present disclosure, ethical concerns implicated with the use of eggs to prepare pluripotent stem cells such as embryonic stem cell can be resolved. And, because the plant stem cell extract unharmful to human is used, pluripotent stem cells with proven safety can be prepared and they may be used to develop immunocompatible cell therapy agents suited for individuals. In addition, by pluripotent stem cells from individuals having diseases, the present disclosure will be very useful in studying the cause of diseases and devolving therapeutic strategy.
