The present invention provides a kit, a method of fabrication of the kit and a method of use of the kit for facilitating the fabrication of a patient-specific implant such as a cranial implant. In a preferred embodiment, the kit 30 includes a thermo-formed plastic sheet 32, a portion 34 of which is formed of PP plastics to the three dimensional contour of a bone structure of a specific patient. The thermo-formed sheet 32 optionally doubles as a container 36 for the remaining elements of the kit, which include bone cement 40a, 40b (typically in two part form, each part contained in a separate container device), and, optionally, disposable forming and/or mixing aids 42 such as a spatula. A kneading recess 44 is also formed in the thermoformed sheet 32 of the kit 30. A sheet 46 is adhered via adhesive 48 and extends between flanges 50 of the thermo-formed sheet, to seal and keep sterilized the components 40a, 40b and 42 and the mould recess (shaping form) 34 of the kit 30 within the container 36.
