BIOGEN IDEC INTERNATIONAL NEUROSCIENCE GMBH;UNIVERSITY OF ZURICH
发明人:
WEIHOFEN, ANDREAS,GRIMM, JAN,HOCK, CHRISTOPH,NITSCH, ROGER,SU, LIHE,WEINREB, PAUL
申请号:
CA2839563
公开号:
CA2839563C
申请日:
2012.06.22
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Provided are anti-human a-synuclein-specific binding molecules, e.g., antibodies or antiben-binding fragments, variants or derivatives thereof, as methods related thereto. Further provided are anti-human a-synuclein binding molecules which bind to specific N-terminal and C-terminal epitopes on human a-synuclein. The binding molecules described herein can be used in pharmaceutical and diagnostic compositions for a-synuclein targeted immunotherapy and diagnosis, respectively.