Jinjun Shi,Frank Alexis,Matteo Iannacone,Elliott Ashley Moseman,Pamela Basto,Robert S. Langer,Omid C. Farokhzad,Ulrich von Andrian,Elena Tonti
申请号:
US13123884
公开号:
US08562998B2
申请日:
2009.10.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface. The nanocarriers are capable of targeting antigen presenting cells when administered to a subject. The invention provides pharmaceutical compositions comprising nanocarriers. The present invention provides methods of designing, manufacturing, and using nanocarriers and pharmaceutical compositions thereof.