PROBLEM TO BE SOLVED: To provide an extract from inflamed rabbit skin inoculated with vaccinia virus and a formulation etc. containing the extract as an active ingredient, which have greater stability in quality.SOLUTION: By using the amount of N-acetyl neuraminic acid contained in the extract from inflamed rabbit skin inoculated with vaccinia virus and the formulation containing the extract as an index, greater stability in quality of the extract and the formulation can be ensured for each production lot. The extract from inflamed rabbit skin inoculated with vaccinia virus and the formulation containing the extract, which are produced in this manner so as to have greater stability in quality, are extremely useful with effectiveness and safety more rigorously secured.SELECTED DRAWING: None
