pharmaceutical composition of derivatives of (3 - hydroxy - 2 - 4 - piron) methyl] - amina and agents demetilanti dna and their use as anti cancer drugs
The present invention concerns pharmaceutical compositions comprising compounds with general formula I or poly-alkyl-bis-maltolic molecules and in particular derivatives of [(3-hydroxy-4-pyron-2-yl)methyl]-amine in combination with DNA demethylating agents as anti-neoplastic drugs. In particular, for the preparation of a medicament for the treatment of neoplastic pathologies.