VALENZANO, KENNETH, JOSEPH,CROWLEY, JOHN,KHANNA, RICHIE,FLANAGAN, JOHN
申请号：
EP13757576
公开号：
EP2823043A4
申请日:
2013.03.07
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The present application provides for compositions comprising high concentrations of acid &alpha；-glucosidase in combination with an active site-specific chaperone for the acid &alpha；-glucosidase, and methods for treating Pompe disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an acid &alpha；-glucosidase enzyme formulation.
