Robin EDWARDS,William J. GEESE,Danielle M. GREENAWALT
申请号：
US16617725
公开号：
US20200109204A1
申请日:
2018.06.01
申请国别(地区):
US
年份:
2020
代理人:
摘要：
This disclosure provides a method for treating a subject afflicted with tumor, which method comprises administering to the subject an antibody or an antigen-binding portion thereof that specifically binds to a Programmed Death-1 (PD-1) receptor and inhibits PD-1 activity. In some embodiments, the tumor is derived from a non-small cell lung cancer (NSCLC). In some embodiments, the tumor expresses Programmed Death Ligand 1. In some embodiments, the subject carries a wild-type STK11 gene.
