Bemis, Jean,Disch, Jeremy S.,Vu, Chi B.,Milne, Jill,Xie, Roger,Armistead, David,Salzmann, Thomas,Nunes, Joseph J.,Ng, Pui Yee
申请号：
AU2006278505
公开号：
AU2006278505B2
申请日:
2006.08.04
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
Provided herein are benzothiazol and thizolopyridine derivatires which are sirtuin-modulating compounds and methods of use thereof . The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/ or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benfit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent .
