Anders Høgset;P{dot over (a)}l Kristian Selbo;Anette Weyergang;Kristian Berg
发明人:
Anders Høgset,Anette Weyergang,P{dot over (a)}l Kristian Selbo,Kristian Berg
申请号：
US13001750
公开号：
US09241996B2
申请日:
2009.06.26
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to a method for enhancing the activity of kinase inhibitors in target cells, and more specifically for enhancing the activity of tyrosine kinase inhibitors (TKIs), said method comprising contacting a cell with a kinase inhibitor and a photosensitizing agent and irradiating said cell with light of a wavelength effective to activate the photosensitizing agent, and to the use of this method for enhancing the effects of kinase inhibitors or kinase inhibitor-based drugs in particular to achieve cell death, for example, in cancer treatment and other diseases or conditions in which kinase inhibitors, such as TKIs, have a beneficial effect.
