The present invention relates to a minimally invasive surgical instrument having a bent shaft, and more particularly to a minimally invasive surgical instrument in which at least a part of a shaft includes a bend. According to one aspect of the invention, there is provided a minimally invasive surgical instrument comprising: a shaft； an end effector connected to one end of the shaft； a joint unit interposed between the shaft and the end effector； and a plurality of wires connected to the joint unit to enable the end effector to carry out joint motion, wherein the shaft comprises at least one bend, and the at least one bend may transmit therein force to operate the end effector in a roll direction, independently of the shaft. The present invention relates to a minimally invasive surgical instrument having a bent shaft, and more particularly, to a minimally invasive surgical instrument in which at least a portion of a shaft is curved. A minimally invasive surgical instrument according to one embodiment of the present invention comprises: a shaft； an end effector connected to one end of the shaft； an articulation unit interposed between the shaft and the end effector； and a plurality of wires connected to the articulation unit so as to enable the end effector to move in an articulating manner. The shaft has at least one curve, and said at least one curve is capable of independently transmitting force to the inside of the end effector such that the end effector may operate in a rolling direction.
