HOTZEL, Isidro,JUNTTILA, Teemu T.,LI, Ji,SCHEER, Justin M.,DICARA, Danielle Marie,ELLERMAN, Diego,SPIESS, Christoph,CARTER, Paul
申请号:
PE0027232017
公开号:
PE03302018A1
申请日:
2016.06.16
申请国别(地区):
PE
年份:
2018
代理人:
摘要:
This referred to a similar anti FC Receptor Antibody (anti fcrh5 Antibodies including fcrh5), comprising a binding domain and a domain Binding to fcrh5 CD3 (cluster of Differentiation 3)Such as T Cell dependent Antibody biespecificos fcrh5 (TDB).It also relates to a composition containing Same, and Methods for using them for the treatment of Cell proliferative disorders, such as positive cancers to fcrh5 or multiple myelomaEsta referido a un anticuerpo similar al receptor anti-Fc 5 (FcRH5) incluso anticuerpos anti-FcRH5, que comprenden un dominio de union a FcRH5 y un dominio de union a CD3 (cumulo de diferenciacion 3), tales como anticuerpos biespecificos dependientes de celulas T (TDB) de FcRH5. Tambien se refiere a una composicion que lo comprende y metodos para utilizarlos para el tratamiento de trastornos proliferativos celulares, tales como canceres positivos a FcRH5 o mieloma multiple