Disclosed herein are methods of treating benign, pre-cancerous, or non-metastatic tumors using an anti-VEGF-specific antagonist. Also disclosed are methods of treating a subject at risk of developing benign, pre-cancerous, or non-metastatic tumors using an anti-VEGF-specific antagonist. Also disclosed are methods of treating or preventing recurrence of a tumor using an anti-VEGF-specific antagonist as well as use of VEGF-specific antagonists in neoadjuvant and adjuvant cancer therapy.本文中揭示使用抗VEGF-特異性拮抗劑治療良性、癌前或非轉移性腫瘤之方法。本文中亦揭示使用抗VEGF-特異性拮抗劑治療處於發生良性、癌前或非轉移性腫瘤危險之個體的方法。本文中亦揭示使用抗VEGF-特異性拮抗劑治療或防止腫瘤復發之方法,以及VEGF-特異性拮抗劑在先導性輔助及輔助癌症療法中之用途。