Within this disclosure are new methods of monitoring compositional changes of a body. In one embodiment, the methods comprise three-dimensional models of a body. In one embodiment, two-dimensional MRI images are used to create a three-dimensional model of a body. In one embodiment, the three-dimensional model is segmented and landmarked to provide reference points for monitoring changes. In some embodiments, volumetric values are calculated to provide data about changes the body has undergone. In one embodiment, the body is a human body.