CORNELIS MARIA PETRUS VAN DUN,CECILIA LUCIA CLARA LELIVELT,SARA MOVAHEDI
申请号：
NL2015752
公开号：
NL2015752B1
申请日:
2015.11.09
申请国别(地区):
NL
年份:
2017
代理人:
摘要：
The present invention relates to a mutant plant of the Cucurbitaceae family comprising a modified CENP-C gene, which mutant plant when crossed to a wild-type plant having 2n chromosomes produces progeny, at least 0.1% of which have 5 n chromosomes. The modification comprises for example a mutation in the CENP-C gene that leads to the occurrence of a premature stop codon or to a non-conservative amino acid change in the C-terminal region of the encoded protein. The plant is for example a Cucumis sativus plant and the modified CENP-C gene encodes a modified CENP-C protein that comprises at least one not-tolerated amino acid change or a premature stop codon in the C-terminal region, when compared to the CENP-C protein of SEQ ID No:1, in particular a mutation selected from E674K and S650N. The plant may also be a Cucumis melo plant wherein the modified CENP-C gene encodes a modified CENP-C protein that comprises at least one not-tolerated amino acid change or a premature stop codon in the C-terminal region, when compared to the CENP-C protein of SEQ ID No:2.
