Fischman, Alan J.,Shoup, Timothy M.,Elmaleh, David
申请号：
AU2011203177
公开号：
AU2011203177B2
申请日:
2011.06.29
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2011203177B220120426.pdf#####Catalytic Radiofluorination Abstract One aspect of the present invention relates to a method of preparing radiofluorinated substituted alkyl, cycloalkyl, aryl, and alkenyl compounds. In a preferred embodiment, 5 potassium fluoride-18 is used. Another aspect of the invention relates to arylphosphonium compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the phosphonium compound is sa tetraaryl phosphonium salt. Another aspect of the present invention relates to a method of obtaining a positron emission image of a mammal, comprising the steps of administering to a mammal a 1o compound of the invention, and acquiring a positron emission spectrum of the mammal.
