‘Macane005’ is a new and distinctive variety of Anemone hupehensis Lemoine × A. rupicola Cambess plant which is characterized by a compact growth habit, white flowers with the tepals alternating between dark pink and white on the lower surface semi-double flowers, and early flowering. The new variety propagates successfully by stem cuttings and tissue culture and has shown to be uniform and stable in the resulting generations from asexual propagation.