Colin M. Tice;Yuanjie Ye;Katerina Leftheris;Zhenrong Xu;Linghang Zhuang;Suresh B. Singh;Frank Himmelsbach;Matthias Eckhardt
发明人:
Matthias Eckhardt,Frank Himmelsbach,Katerina Leftheris,Suresh B. Singh,Colin M. Tice,Zhenrong Xu,Yuanjie Ye,Linghang Zhuang
申请号:
US13703708
公开号:
US08933072B2
申请日:
2011.06.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are compounds represented by Formula (I):or pharmaceutically acceptable salts, enantiomers or diastereomers thereof. Also disclosed are pharmaceutical compositions comprising the compounds of Formula (I) or pharmaceutically acceptable salts, enantiomers or diastereomers thereof for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. Values for the variables of Formula (I) are defined herein.