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Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
专利权人:
Rudolf Johannes Damhuis;Stephen Newman
发明人:
Stephen Newman,Rudolf Johannes Damhuis
申请号:
US11815890
公开号:
US09365905B2
申请日:
2006.02.06
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A process for forming lactose suitable for use in a pharmaceutical formulation comprises providing a plurality of lactose particles containing no more than 10% w/w of lactose particles having a volume average particle size of about 70 microns or less; milling the plurality of lactose particles to yield a plurality of milled lactose particles with an average particle size, (D50), ranging from about 50 microns to about 100 microns; and classifying the plurality of milled lactose particles into at least two fractions comprising a fine fraction and a coarse fraction wherein the fine fraction has an average particle size, (D50), ranging from about 3 microns to about 50 microns, and the coarse fraction has an average particle size, (D50), ranging from about 40 microns to about 250 microns.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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