A NOVEL COMPOUND FOR THE TREATMENT OF EWING SARCOMA AND HIGH-THROUGHPUT ASSAYS FOR IDENTIFYING SMALL MOLECULES THAT MODULATE ABERRANT CHROMATIN ACCESSIBILITY

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专利权人:

THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

发明人:

DAVIS, Ian,JIN, Jian,JANZEN, William P.,PATTENDEN, Samantha,JAYAKODY, Chatura

申请号：

USUS2016/028627

公开号：

WO2016/172332A1

申请日:

2016.04.21

申请国别(地区):

WO

年份:

2016

代理人:

摘要：

The present invention provides a compound useful for the treatment of cancer, and in particular, treatment of Ewing sarcoma. The present invention further provides an assay for identifying a compound that modulates chromatin activity of EWS-FLI1.La présente invention concerne un composé utile pour le traitement du cancer, et en particulier, le traitement du sarcome dEwing. La présente invention concerne, en outre, un dosage permettant didentifier un composé qui module lactivité de la chromatine dEWS-FLI1.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/