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TREATMENT AND PREVENTION OF NEURONAL CELL LOSS USING L-ORNITHINE IN COMBINATION WITH AT LEAST ONE OF PHENYLACETATE AND PHENYLBUTYRATE
专利权人:
INC.;OCERA THERAPEUTICS
发明人:
Christopher F. Rose,Marc-André Clément,Cristina R. Bosoi,Mariana Macedo Oliveira,Mélanie Tremblay,Chantal Bémeur
申请号:
US15751442
公开号:
US20200206174A1
申请日:
2016.09.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are methods of treating and preventing neuronal cell loss in a subject using ornithine in combination with phenylacetate or phenylbutyrate. In some embodiments, the subject has received or will receive a surgical procedure (for example, liver transplantation) for treating a liver disease. In some embodiments, the subject suffers from a liver disease and hypotension.
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