Immunomodulatory compositions containing immunostimulatory sequences linked to antigens and methods of using the compositions

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专利权人:

ダイナバックス テクノロジーズ コーポレイション

发明人:

タック，スティーブン,バン ネスト，ゲイリー,タック,スティーブン,バン ネスト,ゲイリー

申请号：

JP2001537981

公开号：

JP5543050B2

申请日:

2000.11.15

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The invention provides classes of immunomodulatory compositions which comprise an average of one or more immunostimulatory sequence (ISS) containing polynucleotide conjugated, or attached, to antigen. The extent of conjugation affects immunomodulatory properties, such as extent of antigen-specific antibody form ration, including Th1-associated antibody formation, and thus these various conjugate classes are useful for modulating the type and extent of immune response. The invention also includes methods of modulating an immune response using these compositions.

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中国工程科技知识中心

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http://www.ckcest.cn/home/