#$%^&*AU2017258901A120180719.pdf#####METHODS FOR PREDICTING DRUG RESPONSIVENESS IN CANCER PATIENTS ABSTRACT The present invention features methods, devices, and kits for detecting a level of one or more 5 biomarkers in a patient having cancer or determining the responsiveness of a patient having cancer to a treatment, such as treatment with a secretory phospholipase A2 (sPLA2) hydrolysable, cisplatin-containing liposome. The invention further includes methods of treating a patient having cancer by administering, e.g., the liposome.FIG. 1 Predicted sensitivity 0 20 40 60 80 100 I I I I II AML - ED ALL S CLL -- MM - SIM WM - CD EM MDS - ooCm CMLCP DLBCL - o -m CTCL - o IJSIZnmaaInn- - so PTCL Hodgkin -- HCC - o-@IHCervix - EMmD-G Prosta RCC - -e Eso - e- ~ xm - -------------- o Melan Glioma - m - m Pancreas - o -se ------ e a oo Ovary - (M e D-o GIST -e ei105 Sarcoma Breast - e-cwe ERpos --NSCLC - o--0 _____ - E Colon - 0wM- -use- --e e- o Bladder - ocm SCCHN - x@ >；- -Page 1 / 1
