This invention relates to a kind of C- aryl glycoside derivatives, its pharmaceutical compositions, preparation methods, and uses thereof. The preparation method comprises: method 1: in a solvent, deprotecting the acetyl protecting groups of compound 1-f in the presence of a base method 2: 1) compound 2-g reacts withvia Mitsunobu reaction 2) deprotecting the acetyl protecting groups of compound 2-f obtained from step 1 method 3: 1) compound 2-g reacts withvia nucleophilic substitution reaction 2) deprotecting the acetyl protecting groups of compound 3-f obtained from step 1. The pharmaceutical composition comprises a kind of C- aryl glycoside derivatives its pharmaceutically acceptable salts and/or prodrugs thereof and excipient thereof. This invention further relates to a kind of C- aryl glycoside derivatives, its pharmaceutically acceptable salts or pharmaceutical compositions thereof for the use in preparation of a SGLT inhibitor. The C- aryl glycoside derivatives of this invention provides a new direction for the study of SGLT inhibitors.
