A ligation device comprises a clamp and a conveying unit. The clamp comprises a clip and a tightening tube to tighten a rear end of the clip therein, the clip comprises two clamping arms. The conveying unit comprises a traction line, a conveying tube and a control handle, the traction line runs through the conveying tube, the control handle is connected with a rear end of the conveying tube and a rear end of the traction line. At least one bearing piece is arranged at a tail of the clip and can be deformed or broken under a certain pressure, the bearing piece is assembled to form a hole, the traction line runs through the hole and a front end of the traction line is blocked by the bearing piece.