Rosanne M. Crooke,Mark J. Graham,Susan M. Freier,Marc Lim,Andrew Dibble
申请号:
US15855203
公开号:
US20180256629A1
申请日:
2017.12.27
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof.