This invention the bisuhosuhoneto activator offers the manner which is prescribed to the patient with lung path with the pyrazolone derivative and combined use. In addition, this invention offers the medicine constituent in order to use at the time of executing the manner which you follow the execution feature of this invention. As for the said manner and the constituent which you follow the execution feature of this invention, use at the time of various applying which such as remedy of the bone absorption diseased sick condition differ is discovered, but it is not something which is limited in these.本発明は、ビスホスホネート活性剤をピラゾロン誘導体と併用で肺経路によって患者に投与する方法を提供する。また、本発明は、本発明の実施態様にしたがう方法の実施において用いるための医薬組成物を提供する。本発明の実施態様にしたがう該方法および組成物は、骨吸収疾患病態の治療などのさまざまな異なる適用においての使用が見出されるが、これらに限定されるものではない。
