The invention relates to amine substituted methanesulfonamide derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.本發明係關於以被胺取代之甲基磺醯胺衍生物做為類香草素受體之配位體,含此類化合物之醫藥劑型,及使用此類化合物治療及/或預防疼痛及其它疾病/或失調。