Elmore, Steven,Souers, Andrew,Wang, Li Chun,Ghayur, Tariq,Perper, Stuart J.
申请号:
AU2016204396
公开号:
AU2016204396A1
申请日:
2016.06.27
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2016204396A120160714.pdf#####METHODS OF TREATMENT USING SELECTIVE BCL-2 INHIBITORS Abstract This invention pertains to methods of treating systemic lupus erythematosus, lupus nephritis or Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2 anti apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bel-XL-