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AGENT ANTITUMORAL ET INHIBITEUR DE BROMODOMAINE
专利权人:
FUJIFILM CORPORATION;FUJIFILM TOYAMA CHEMICAL CO., LTD.;NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
发明人:
MAKITA, KEIKO,SAEKI, KAZUNORI,TANAKA, TADASHI,FUJINO, MASATAKA,NATSUME, TOHRU,FURUYA, KENTARO
申请号:
CA3048602
公开号:
CA3048602A1
申请日:
2017.12.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention addresses the problem of providing an antitumor agent that is exceptional as a treatment agent for the prevention and/or treatment of tumors involving bromodomains, and providing a bromodomain inhibitor that is useful as a treatment agent for diseases or conditions involving bromodomains. An antitumor agent and bromodomain inhibitor containing a compound represented by the general formula [in the formula, R1 represents a C1-6 alkyl group, etc.; R2 represents a hydrogen atom, etc.; R3 represents a halogen atom, etc.; Z1, Z2, and Z3 represent CH, etc.; X1 represents CONH, etc.; ring A represents a phenyl group, etc.; R4 represents a halogen atom, etc.; and m represents an integer of 0-5] have exceptional bromodomain inhibitory activity and are useful as treatment agents for the prevention and/or treatment of tumors involving bromodomains.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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