COMPOSITIONS OPHTALMIQUES AQUEUSES TOPIQUES CONTENANT UN DERIVE DE 1H-INDOLE-1-CARBOXAMIDE, ET LEUR UTILISATION POUR LE TRAITEMENT D'UNE MALADIE OPHTALMIQUE
GHOSH, MALAY,ADAMS, CHRISTOPHER MICHAEL,DODD, STEPHANIE KAY,POOR, STEPHEN HEDRICK
申请号：
CA2897949
公开号：
CA2897949A1
申请日:
2014.06.04
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention is directed to the provision of a multi-dose topical ophthalmic composition containing a 1H-indole-1-carboxamide and use thereof for treatment of ophthalmic disease. More specifically the present invention is directed to a multi-dose aqueous ophthalmic composition (e.g., a solution, a suspension, an emulsion or the like) containing a 1H-indole-1-carboxamide (e.g., N-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6-((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide) and use thereof for treatment of an ophthalmic disease at the back of the eye such as age related macular degeneration (AMD).
