The present invention relates to shigella IpaB803 protein and preparation thereof. The present invention also relates to nucleic acid encoding shigella IpaB803 protein. The present invention further discloses the use of shigella IpaB803 protein to trigger apoptosis. In particular, the present invention relates to the use of shigella IpaB803 protein in preparing medicine for facilitating apoptosis. The present invention also provides a method of screening an epidemic strain for stable expression of shigella IpaB803 protein.本發明係關於一種志賀氏桿菌IpaB803蛋白質及其製造方法。本發明亦關於編碼志賀氏桿菌IpaB803蛋白質之核酸序列。本發明進一步描述志賀氏桿菌IpaB803蛋白質用於引發細胞程序死亡(凋亡)之用途,特別地,係關於志賀氏桿菌IpaB803蛋白質用於製備供促使細胞死亡之醫藥品的用途。本發明亦提供一種用於篩檢穩定表現IpaB803蛋白質之志賀氏桿菌流行株的方法。
