The present invention is concerned with an adhesive system. The system comprises a guest copolymer portion and a host copolymer portion. The guest copolymer portion includes 3,4-dihydroxy-L-phenylalanine (DOPA) acting as an adhesive moiety, a recognition molecule and a hydrophobic molecule connecting the adhesive moiety and the recognition molecule. The host copolymer portion includes a macrocyclic host molecule from a host family of supramolecules for specifically binding with the guest copolymer at the recognition molecule, and a polymer with temperature dependent wettability.