-28- METHOD OF EXTRACTING AND MANUFACTURING OYSTER MEAT EXTRACT USING A method of extracting and manufacturing an oyster meat extract using pressurized or depressurized extraction, the method comprising: an extraction step of storing oyster meat in an extraction container where a solution is stored and extracting, within the extraction container, the oyster meat extract from the oyster meat a step of concentrating the oyster meat extract extracted in the extraction step an agitation step of adding an ethanol solution to the concentrated oyster meat extract and performing agitation a separation step of performing separation into a precipitate and a supernatant solution after a predetermined time after the agitation and a concentration step of concentrating the obtained precipitate, wherein the extraction step is a step in which the extraction is performed in a state where a pressure is increased to a normal pressure or more or in a state where a pressure is reduced to the normal pressure or less such that it is possible to perform the extraction from all portions without damaging the oyster meat and extract a large number of types of active ingredients of the oyster meat extract the agitation step and the separation step are a centrifuging step using a continuous centrifuge, the continuous centrifuge includes: a storage member that has a storage space portion therewithin a rotary shaft portion that is arranged within the storage member and that is configured to be rotatable with a longitudinal direction being a center shaft direction a rotary member that has a plurality of rotary blades spaced a distance apart from an outer circumference of the rotary shaft portion a rotary means that rotates the rotary member an injection portion that continuously injects a solution to be separated into the storage space portion a discharge portion that centrifuges the solution injected from the injection portion and that continuously discharges a separated fluid from a side portion