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Use of alginate matrices to control cell growth
专利权人:
Jan Egil Melvik
发明人:
Jan Egil Melvik,Michael Dornish
申请号:
US12854999
公开号:
US08541017B2
申请日:
2010.08.12
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Methods of inhibiting proliferation of a plurality of proliferating cells are disclosed. Methods of inhibiting cell overgrowth on compositions that are in an animals body are disclosed. Methods of inhibiting cell overgrowth on a device that is in an animals body are disclosed. Devices that have on their exterior surface an alginate matrix that comprises Strontium are disclosed. Compositions comprising an alginate body and alginate sheets that each comprise a single layer of cells coating the exterior surface of the alginate body are disclosed. Methods of preparing an artificial tissue are disclosed. Devices comprising cells encapsulated within an alginate matrix and/or maintained as a monolayer on an alginate body, and methods of making and using the same are disclosed. Methods of coating compositions and devices are disclosed.
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