Disclosed herein is a transdermal delivery system comprising galantamine or its salt as an active ingredient. Also provided are methods of delivering a therapeutically effective amount of galantamine to a subject for the treatment of a disease condition. The disease condition includes a neurological condition such as Alzheimer’s disease. Kits including the transdermal delivery system and methods of making such delivery system are also provided.本發明揭示一種透皮釋放系統,其以加蘭他敏或其醫藥用鹽類作為活性成分。同時也提供一種方法用以將具有療效劑量的加蘭他敏供給予受試者以治療疾病狀況。所述疾病包含神經性疾病,例如:阿茲海默症。另外,本發明的試劑組包含所述透皮釋放系統和製造所述透皮釋放系統的方法。