A biological containment and transport carrier apparatus which includes a base layer having an inner surface and an opposing outer surface, a top layer having an inner surface and an opposing outer surface, a perimeter of the top layer is coupled to a perimeter of the base layer to form a sealed bag, and a zipper formed within the top layer configured to open and close an insertion flap to provide access to a cavity formed between the base layer and the top layer, wherein a portion of the top layer around the zipper is configured to fold inside out around a table to secure the base layer to the table.