Sirna conjugate and preparation method thereof

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专利权人:

发明人:

申请号：

EP13159602.5

公开号：

EP2626427A2

申请日:

2010.05.13

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Provided are an siRNA-polymer conjugate, wherein siRNA is a survivin specific siRNA. The conjugate of the present invention can improve the in vivo stability of siRNA, thereby achieving an efficient delivery of therapeutic siRNA into cells and exhibiting the activity of siRNA even with a small dose of a relative low concentration. Therefore, the conjugate can advantageously be used as not only an siRNA treatment tool for cancers and other infectious disease, but also a novel type siRNA delivery system.

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中国工程科技知识中心

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http://www.ckcest.cn/home/