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AAV1-caspase gene therapy induced pyroptosis for the treatment of tumors
专利权人:
发明人:
Gary J. Brenner,Xandra O. Breakefield,Giulia Fulci
申请号:
US14169112
公开号:
US09644215B2
申请日:
2014.01.30
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Described herein are compositions and methods for treating, inhibiting, preventing, reducing the severity of and/or reducing the progression of schwannoma, as well as any disease or physiological disease-state in which schwannoma plays a role. The compositions comprise an rAAV vector that includes a caspase-1 gene or a variant thereof and a Schwann cell specific promoter.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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