Gary J. Brenner,Xandra O. Breakefield,Giulia Fulci
申请号:
US14169112
公开号:
US09644215B2
申请日:
2014.01.30
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Described herein are compositions and methods for treating, inhibiting, preventing, reducing the severity of and/or reducing the progression of schwannoma, as well as any disease or physiological disease-state in which schwannoma plays a role. The compositions comprise an rAAV vector that includes a caspase-1 gene or a variant thereof and a Schwann cell specific promoter.