A device (20) for the topical dispensing of a powder, typically a powder medicament, comprises, or is adapted to be coupled to, a powder receptacle (31) and a gasflow generator. The gasflow generator is adapted, in use, to cause gas to flow through the device (20), which further comprises an agitator by which the powder and/or the powder receptacle (31) can be mechanically agitated. Actuation of the gasflow generator, which causes gas to flow through the device (20) and to entrain powder from the powder receptacle (31), thereby to dispense powder from the device (20), is accompanied by actuation of the agitator, causing the powder receptacle (31) to be mechanically agitated, thereby facilitating the release of powder from the powder receptacle (31).
