Boehm, Marcus F.,Martinborough, Esther,Moorjani, Manisha,Tamiya, Junko,Huang, Liming,Yeager, Adam R.,Brahmachary, Enugurthi,Fowler, Thomas,Novak, Andrew,Meghani, Premji,Knaggs, Michael
申请号：
AU2012352349
公开号：
AU2012352349B2
申请日:
2012.12.12
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The invention relates to compounds that are characterized by possessing at least four cycles (A-C and phenylene ring). Such compounds modulate the glucagon-like peptide 1 (GLP-1) receptor and have a therapeutic use that includes diseases such as diabetes, obesity and excessive appetite. The compounds act as modulators or potentiators of the GLP-1 receptor, or act with receptor ligands including GLP-1 peptides GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide. Claimed are compounds of the fol lowing genera structure (" ﹋ "
