CHO, YONG BAIK,조용백,KANG, MOON KYU,강문규,JUNG, IN HO,정인호,HUR, JONG HYUN,허종현,KIM, SOON HAN,김순한,LEE, JEONG HUN,이정훈,KANG, JI YUN,강지윤,JUNG, KYOUNG CHUL,정경철,LEE, JE YOUNG,이제영,KIM, SEUL KI,김슬기
申请号：
KR1020110012410
公开号：
KR1020120094563A
申请日:
2011.02.11
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A composition for prevention or treatment of respiratory diseases containing mixed herb extracts of rhei undulati rhizoma and cnidii rhizome are provided to improve 5- lipoxygenase inhibiting activities, airway narrowing inhibiting activities, airway inflammation inhibitory actions and ear edema antiphlogistic actions. CONSTITUTION: A composition for prevention or treatment of respiratory diseases contains the extract, which is manufactured by extracting the mixture of rhei undulati rhizoma and cnidii rhizome using low grade alcohol having 1-4 carbons or 10-95% thereof, as an active ingredient. The extract is refined by ethyl acetate, and dichloromethane or butanol. The herb medicine mixing weight rate of Cnidii Rhizoma to Rhei undulati Rhizoma is 0.1:1-10:1. A health supplement for prevention or treatment of respiratory diseases contains the extract, which is manufactured by extracting the mixture of rhei undulati rhizoma and cnidii rhizome using low grade alcohol having 1-4 carbons or 10-95% thereof, as an active ingredient.본 발명은 천궁(Cnidii Rhizoma) 및 종대황(Undulatum Rhubarb)의 혼합 생약 추출물을 유효성분으로 함유하는 호흡기 질환의 예방 또는 치료제 및 이의 제조방법에 관한 것으로, 상기 천궁 및 종대황의 혼합 생약 추출물은 5-리폭시게나제 억제 활성, 기도수축억제 활성, 기도염증 억제 작용 및 귀부종 소염 효과가 우수함을 확인하여, 천식, 만성폐쇄성폐질환, 급만성기관지염, 알레르기 비염, 진해 거담, 급성하기도 감염증(기관지염 및 세기관지염), 인후염, 편도염, 후두염과 같은 급성상기도감염증 등의 호흡기질환의 예방 또는 치료에 유용한 것으로 확인된다.
