KAPPA-OPIATE AGONISTS FOR THE TREATMENT OF IRRITABLE COLD SYNDROME OF PREDOMINANT OR ALTERNATED DIARRHEA

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专利权人:

TIOGA PHARMACEUTICALS INC.

发明人:

ALLEN MANGEL

申请号：

BRPI0809651

公开号：

BRPI0809651A2

申请日:

2008.03.07

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The present invention concerns methods useful in treating one or more subtypes of irritable bowel syndrome (IBS), or useful in treating diarrhea. The invention relates to the use of peripherally selective kappa-opiate agonists, especially N-methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidin-1-yl)ethyl]-2,2-diphenylacetamide and/or a pharmaceutically acceptable salt thereof for treating a subject having IBS with alternating diarrhea and constipation (IBS-A).

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