PROBLEM TO BE SOLVED: To provide a novel skin external preparation containing oil bodies that store Calophyllum inophyllum seed oil as a use form of Calophyllum inophyllum seed oil that has not been studied thus far, and also to provide a method of producing the skin external preparation.SOLUTION: A separation method utilizing the property that oil bodies spontaneously aggregate in water extract, specifically a floating/sedimentation method that does not require centrifugation and/or a filtration method using a filter medium having a particle retention capacity of about 5 to 50 microns is used to obtain oil body aggregates in a hydrated state from an aqueous extract of non-dried seeds of Calophyllum inophyllum. By utilizing the effect of the seed oil oozing out of the oil bodies by contact with the skin, the oil body aggregate hydrate is used as a skin external preparation for penetrating the skin with Calophyllum inophyllum seed oil. Because the oil bodies contain phospholipids that function as a skin moisturizing ingredient, the skin external preparation has a higher moisturizing effect in addition to the various effects of the Calophyllum inophyllum seed oil.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2020,JPO&INPIT【課題】テリハボク種子油の今までに検討されていない利用形態として、テリハボク種子油を貯蔵するオイルボディを含有する新規な皮膚外用剤及び皮膚外用剤の製造方法を提供すること。【解決手段】テリハボクの非乾燥種子の水抽出液から、オイルボディが水抽出液の中で自発的に凝集する性質を利用した分離法、具体的には、遠心操作が不要な浮上／沈殿法及び／又は粒子保持能が５－５０ミクロン程度のろ過材を用いたろ過法によって、オイルボディの凝集体を水和した状態で得る。皮膚との接触によってオイルボディから種子油が滲出してくることを利用し、このオイルボディ凝集体水和物を、皮膚にテリハボク種子油を浸透させるための皮膚外用剤として使用する。オイルボディは皮膚の保湿成分として機能するリン脂質を含むため、この皮膚外用剤はテリハボク種子油のもつさまざまな効能に加えてより高い保湿効果を持つ。【選択図】図１
