A catheter assembly 10 comprising a main body 100 having a first opening 110, a second opening 120 and a cavity 130 defined therebetween configured to receive a lubricant 140. A catheter tube 220 extends through the first opening 110, the cavity 130 and the second opening 120. A seal 160 configured to fluidly seal the second opening 120 when the catheter tube 220 is extended through the second opening 120. The main body comprises one or more alignment portions 170 configured to radially constrain the catheter tube 220 when it is received by the cavity 130. The alignment portions 170 extend radially inwardly from an internal surface of the main body 100. The assembly may also comprise a catheter grip 210 which may fluidly seal the first opening 110. The alignment portions 170 may be discontinuous along the axial length of the cavity 130. The lubricant 140 may comprise a gel. A container 300 may hermetically seal at least a portion of the catheter tube 220. The container 300 may be flexible and may comprise a foil. The seal 160 may comprise a flexible or elastomeric material.