Phosphorus substituted group-containing quinoline-like compound of formula (I) are provided in the present invention. The preparation process and application of the compound, and pharmaceutical formulation comprising phosphorus substituted group-containing quinoline-like compound are also disclosed. The compounds are protein kinase inhibitor and can be used for treating protein kinase abnormal activity-associated diseases, such as neoplasm, etc.本發明提供了一類如式(I)所示的含磷取代基的喹啉類化合物，同時還公開了該化合物的製備方法及應用和含所述含磷取代基的喹啉類化合物的藥劑。這類化合物是蛋白激酶的的抑制劑，可用於治療因蛋白激酶活性異常所引起的疾病，例如腫瘤等。
