David Benjamin Jaroch,James E. Chomas,Bryan Pinchuk,Aravind Arepally
申请号:
US15871871
公开号:
US20190298983A1
申请日:
2018.01.15
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A treatment system includes a guide sheath, and a catheter provided with a pressure-controlled element. The pressure-control element preferably includes an expanded configuration adapted to extend across a small feeder vessel branching from the splenic vein. The pressure-control element is positioned with the feeder vessel, and a therapeutic agent is delivered under pressure directly into the feeder vessel, where it is forced to penetrate deep into tissue. Pressure responsive elements for monitoring intravascular pressure are also provided to time delivery of the therapeutic agent for maximum uptake by the target organ. Methods for treating tissues and organs via vascular pathways are provided.