This invention relates to a use of a fermented Glycine max (L.) extract prepared by fermenting a Glycine max (L.) extract in inducing autophagy in a subject. In particular, the fermented Glycine max (L.) extract can be used in preventing and/or treating a disease in which in a subject, such as cancer, diabetes neurodegeneration, steatohepatitis and aging. The invention also relates to a use of the fermented Glycine max (L.) extract in inducing apoptosis in combination with autophagy in a subject.