MAURER, ALEXANDER B.,HOEVELMANN, SASCHA,MARTIN, ELKE,HENTSCH, BERND,GASSEN, MICHAEL,KRAUS, JUERGEN,KRAUSS, ROLF,VINCEK, ADAM-SPENCER
申请号：
CA2491131
公开号：
CA2491131C
申请日:
2003.07.17
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention is directed to compounds of the general formula (I) orpharmaceutical acceptable salts or physiologically functional derivativesthereof wherein: n is a non-aromatic ring system containing two to sevencarbon atoms, wherein the ring system can contain one ore two double bonds； Xis C, CH or CH2； Y is selected from C, CH, CH2, S, NR, CH2-CH2, H2C- -CH, HC- -CH2, C- -CH2, H2C- -C,or C - -C； one or more of the hydrogen atoms canopionally be substituted by one or more substituents R ； each of the dottedlines means a single, a double or triple bond with the exclusion of acombination of a triple with triple bond and a double with a triple bond； R isindependently H, -CN, alkyl, cycloalkyl, aminoalkyl, alkylamino, alkoxy, -OH, -SH, alkylthio, hydroxyalkyl, hydroxyalkylamino, halogene, haloalkyl,haloalkyloxy； R is H, an alkyl or cycloalkyl group； Z is CH, C, or P； p is 0or 1.
