GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH; CHINESE ACADEMY OF SCIENCES
发明人:
Yanmei ZHANG,John Jeffrey TALLEY,Mark G. OBUKOWICZ,Zhengchao TU,Micky TORTORELLA,Yican WANG,Jianqi LIU,Yan CHEN,Xiaorong LIU,Xin LU
申请号：
US15182525
公开号：
US20170020843A1
申请日:
2016.06.14
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention discloses deuterated benzopyran compounds having structure features as shown in Formula (I), or pharmaceutically acceptable salts or stereoisomers thereof, or prodrug molecules thereof. With excellent anti-inflammatory and analgesic effects and the capability to inhibit growth of tumor cells, such compounds are novel COX-2 selective inhibitors. The compounds and pharmaceutically acceptable salts thereof disclosed by the present application can be applied in preparing anti-inflammatory and analgesic drugs and drugs for treating or preventing tumors.
